Artificial intelligence, the virtualization of human activities and biotechnologies emerge as techniques and instruments that are already modifying social organizations and man himself as a species. The future of the human species and the entire system of life will depend on the way in which humans and their form of organization are used and modified. Man as a species and as a historical and cultural subject will have a leading and decisive role in facing the civilizational changes that have already touched our present and announce an uncertain future.